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How Vital Proteins Dominated Amazon's Collagen Market

25+ “How to Sell on Amazon” Courses, Mentorships, and Trainings
Scott Needham
CEO and Founder of SmartScout

When you look at the collagen market on Amazon, one brand stands head and shoulders above the rest: Vital Proteins. Not only does this brand control an impressive 18% market share, but its nearest competitor barely touches 6%. That's a staggering lead.

What's even more remarkable? Vital Proteins only launched ten years ago, starting modestly with a $25,000 investment in a small Chicago facility. Through smart early marketing, especially leveraging micro-influencers, they quickly caught consumer attention. However, the game truly changed when Jennifer Aniston publicly endorsed the brand, transforming Vital Proteins from niche supplement to mainstream powerhouse. The result? A nearly billion-dollar acquisition—proof that savvy brand positioning can create massive value.

Top 10 Collagen Brands on Amazon (by Monthly Revenue):

  • Vital Proteins – $10.6M
  • Ancient Nutrition – $3.7M
  • Sports Research – $3.5M
  • Live Conscious – $3.3M
  • Micro Ingredients – $2.7M
  • Vital Vitamins – $1.9M
  • Orgain – $1.6M
  • Juven – $1.5M
  • Great Lakes Wellness – $1.4M
  • Native Path – $1.0M

The collagen market is extremely competitive, yet there's something unique happening here—every one of these brands is U.S.-based. This isn’t coincidental. Supplement buyers deeply trust brands from the U.S., prioritizing transparency, regulation, and quality.

Ancient Nutrition: A Bold Advertising Strategy


Interestingly, Ancient Nutrition—holding the #2 spot—is significantly outspending its market share. With only 6.4% market share, they're responsible for over 10.6% of the category's total ad spend. While some marketers might call this overspending, there’s a forward-thinking strategy behind it. Collagen is typically taken daily, meaning one-time customers often become long-term subscribers. By aggressively investing in ads now, Ancient Nutrition aims to secure a loyal consumer base for the future. But it’s an expensive gamble, as Amazon’s Advertising API reveals eye-watering CPCs—sometimes even above $10 per click for branded keywords.

Supplements: Science or Fad?


Finally, collagen's explosive popularity raises the classic supplement question: Is this all hype, or is there science backing it? The industry is often plagued by fleeting trends, yet collagen seems to stand out. A growing body of research suggests real benefits, especially for joint, skin, and gut health. Still, discerning consumers—and cautious marketers—remain watchful.

In short, the collagen market offers a fascinating microcosm of modern brand-building: influencer marketing, celebrity endorsements, strategic ad spending, and a powerful consumer preference for domestic brands. Vital Proteins' astonishing rise should remind every marketer of one key lesson: even in a crowded category, strategic positioning can create industry giants almost overnight.

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